General Cell Lines and Cell Cultures
Creative Bioarray OCI-AML-3 cell line, Cat. No. CSC-C9119W, human, 57 years, male, acute myeloid leukemia (AML) FAB M4, NPM1 mutation, DNMT3A R882C, frozen, 37 ℃, 5% CO2
OCI-AML-3 cell line, Cat. No. CSC-C9119W, human, 57 years, male, acute myeloid leukemia (AML) FAB M4, NPM1 mutation, DNMT3A R882C, frozen, 37 ℃, 5% CO2
Brainxell Inc Cortical GABAergic Neurons (Human iPSC-Derived, Male Line, 1M)
Cortical GABAergic neurons derived from iPSC line WC-30, male. Contents: 1 vial of ≥1x10^6 viable cryopreserved cells. Marker Expression: Cortical GABAergic Neurons (BX-0400) have high neuronal purity (>80%) and comprise predominantly inhibitory neurons. Labelling with the pan-neuronal marker MAP2(green) and for GABA (red) highlight the purity of this neuronal product. Function: Cortical GABAergic Neurons exhibit pronounced electrophysiological activity after two weeks in culture, as demonstrated on multi-electrode array (MEA) recording systems. Related diseases: Epilepsy, Alzheimer's Disease, & Schizophrenia. Primary neurotransmitter released: GABA
Lonza Walkersville Tissue Culture Plates, 25 Count
Clear Bottom White Walled Tissue Plates are white walled 96-well plastic plates designed specifically for use with any bioluminescent bioassay kit.Content:25 x Clear Bottom, White-Walled Tissue Culture Plates
ATCC Streptococcus mitis; NS 51; genomic DNA
Genomic DNA from Streptococcus mitis strain NCTC 12261 (ATCC 49456). This product can be used in PCR and other molecular biology applications.
Eurofins Discoverx PathHunter GRPR Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0667C3)
The PathHunter GRPR Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of GRPR via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged GRPR. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting GRPR-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Matched Pair - Total Protein - Human Primary Tumor and Metastatic Tumor Tissue (PM): Stomach, 0.2 x2 mg /PK
BioChain's human total protein matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of total protein isolated from primary tumor and its adjacent normal tissue; PM consists of total protein from primary tumor andcorresponding metastastic tumor. Total proteins in each pair are prepared from the same donor. This product line is designedfor identifying tumor-specific genes and tumor metastasis genes.
Eurofins Discoverx PathHunter CHO-K1 TACR1 β-Arrestin Cell Line, 2 vials. (93-0344C2)
The PathHunter TACR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. substance P) based activation of TACR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR1 and EA-tagged β-Arrestin-2. Activation of TACR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Blood Vessel: Vein, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Eurofins Discoverx PathHunter CHO-K1 mOPRD1 β-Arrestin Cell Line, 2 vials. (93-0611C2)
The PathHunter mOPRD1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. DADLE) based activation of mOPRD1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mOPRD1 and EA-tagged β-Arrestin-2. Activation of mOPRD1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen α1B Adrenergic Receptor Membrane Preparation, 1 vial. (HTS158M)
The ChemiScreen α1B Adrenergic Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of ADRA1B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC Kasumi-1; Leukemia (AML); Human (Homo sapiens)
Kasumi-1 is a myeloblast cell that was isolated from the peripheral blood of an acute myeloblastic leukemia Asian male patient. This cell line was deposited by H Asou in 1989.
ATCC 4T1; Mammary Tumor; Mouse (Mus musculus)
The tumor growth and metastatic spread of 4T1 cells in BALB/c mice very closely mimic human breast cancer. This tumor-derived cell line is an animal model for stage IV human breast cancer. 4T1-induced tumors can be used as a post-operative model as well as a nonsurgical model because the 4T1-induced tumor metastasizes spontaneously in both models with similar kinetics.
ATCC Primary Umbilical Vein Endothelial Cells; Normal, Human
Normal Primary Human Umbilical Vein Endothelial Cells (HUVEC), when grown in Vascular Cell Basal Media supplemented with Endothelial Cell Growth Kit components, provide an ideal cell system to propagate HUVEC in low serum conditions with or without the addition of human recombinant VEGF.
Eurofins Discoverx PathHunter EDNRB Total Internalization U2OS Cell Line, 2 vials. (93-0874C3)
The PathHunter EDNRB Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of EDNRB via detection of localization to the early endosome. The included cell line overexpresses EA-tagged EDNRB and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the EDNRB receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Creative Biolabs MOUSE MC38 TUMOR CELL LINE, Female, C57BL/6, Colorectal Carcinoma, Adherent culture, Epithelial morphology, High mutational burden, Claudin-1, SATB2
MOUSE MC38 TUMOR CELL LINE, Female, C57BL/6, Colorectal Carcinoma, Adherent culture, Epithelial morphology, High mutational burden, Claudin-1, SATB2